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Aerodynamic stability evolution tendency of suspension bridges with spans from 1000 to 5000 m
Frontiers of Structural and Civil Engineering doi: 10.1007/s11709-023-0980-z
Keywords： suspension bridge super long-span finite element model aerodynamic instability aerodynamic configuration
Combustion instability detection using the wavelet detail of pressure fluctuations
JI Junjie, LUO Yonghao
Frontiers in Energy 2008, Volume 2, Issue 1, Pages 116-120 doi: 10.1007/s11708-008-0019-0
Keywords： comparison wavelet approximation pressure transducer general pressure consistent
Progress and Prospect of Seafloor Instability Research
Gao Weijian, Li Wei
Strategic Study of CAE 2023, Volume 25, Issue 3, Pages 109-121 doi: 10.15302/J-SSCAE-2023.03.010
Seafloor instability and secondary submarine geohazards are widely presentHowever, formation mechanisms and controlling factors of seafloor instability are still poorly understoodTo improve the understanding, based on the history and development of seafloor instability, thisengineering geohazards risks, and summarizes popular quantitative analysis methods for seafloor instability, this study proposed the development direction and countermeasures of future seafloor instability
Keywords： seafloor instability submarine geohazards formation mechanisms risk assessment instability analysis
Size-dependent Elastic Instability of Gel CylinderWith Surface Stress
Huang Dianwu,Qiao Ling, Wang Shiji
Strategic Study of CAE 2007, Volume 9, Issue 4, Pages 50-54
The elastic instability of a gel cylinder was researched with classicalThe non-classic boundary condition of the elastic instability has been educed by the energy functional So a criterion equation of the elastic instability can be got.Through the analysis of the equation, it is found that the elastic instability is relevant to the radius
Keywords： gel cylinder elastic instability intrinsic scale surface effect
Modulational Instability of Optical Vortices in Engineered Saturable Media Review
D.G. Pires, N.M. Litchinitser
Engineering 2022, Volume 17, Issue 10, Pages 31-43 doi: 10.1016/j.eng.2022.04.022
Propagation of light beams in turbid media such as underwater environments, fog, clouds, or biological tissues finds increasingly important applications in science and technology, including bio-imaging, underwater and free-space communication technologies. While many of these applications traditionally relied on conventional, linearly polarized Gaussian beams, light possesses many degrees of freedom that are still largely unexplored, such as spin angular momentum (SAM) and orbital angular momentum (OAM). Here, we present nonlinear light–matter interactions of such complex light beams with "rotational" degrees of freedom in engineered nonlinear colloidal media. By making use of both variational and perturbative approach, we consider non-cylindrical optical vortices, elliptical optical vortices, and higher-order Bessel beams integrated in time (HOBBIT) to predict the dynamics and stability of the evolution of these beams. These results may find applications in many scenarios involving light transmission in strongly scattering environments.
Keywords： Optical vortex Orbital angular momentum Modulation instability Turbid media
Underlying mechanism of the hydrothermal instability of Cu
Nadeen Al-Janabi,Abdullatif Alfutimie,Flor R. Siperstein,Xiaolei Fan
Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 1, Pages 103-107 doi: 10.1007/s11705-015-1552-0
Keywords： hydrothermal stability metal-organic framework (MOF) open metal sites (OMSs) dynamic water vapour adsorption
Mechanisms and impacts of chromosomal translocations in cancers
Jing H. Wang
Frontiers of Medicine 2012, Volume 6, Issue 3, Pages 263-274 doi: 10.1007/s11684-012-0215-5
Chromosomal aberrations have been associated with cancer development since their discovery more than a hundred years ago. Chromosomal translocations, a type of particular structural changes involving heterologous chromosomes, have made a critical impact on diagnosis, prognosis and treatment of cancers. For example, the discovery of translocation between chromosomes 9 and 22 and the subsequent success of targeting the fusion product BCR-ABL transformed the therapy for chronic myelogenous leukemia. In the past few decades, tremendous progress has been achieved towards elucidating the mechanism causing chromosomal translocations. This review focuses on the basic mechanisms underlying the generation of chromosomal translocations. In particular, the contribution of frequency of DNA double strand breaks and spatial proximity of translocating loci is discussed.
Keywords： DNA double strand breaks chromosomal translocations genomic instability spatial proximity carcinogenesis
p-Cresyl sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by
Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin
Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 320-329 doi: 10.1007/s11684-016-0463-x
Coronary atherosclerosis is a major complication of chronic kidney disease. This condition contributes to the increased mortality in dialysis patients. p-Cresyl sulfate (PCS) is a prototype of protein-bound uremic toxins that cannot be efficiently removed through routine dialysis procedures. In the present study, ApoE−/− mice that underwent 5/6 nephrectomy were randomly divided into two groups, namely, vehicle-treated group (n = 20) and PCS-treated group (n = 20). Mice were sacrificed for en face and immunohistological analyses after 8 or 24 weeks of high-fat diet. Rat aortic vascular smooth muscle cells (VSMCs) were treated with phosphate buffer solution or 500 µmol/L PCS for in vitro evaluation. PCS-treated mice were observed to suffer increased atherosclerotic lesions after eight weeks of PCS administration. Moreover, 24 weeks of PCS administration also markedly increased the vulnerability index of aortic plaques. PCS was also observed to facilitate the migration and proliferation of VSMCs during the progression of the disease. Moreover, PCS disturbed the balance between matrix metalloproteinases and tissue inhibitor of metalloproteinases within the plaques. Thus, PCS played a vital role in promoting atherogenesis and disturbing the stability of formed plaques probably by targeting VSMCs.
Keywords： p-cresyl sulfate atherosclerosis plaque stability vascular smooth muscle cell
Xie Xianqi,Jia Yongsheng,Yao Yingkang,Sun Jinshan,Wu Xinxia,Liu Changbang
Strategic Study of CAE 2014, Volume 16, Issue 11, Pages 65-71
Keywords： viaduct blasting demolition precision blasting instability model initiation network adverse effects control
Chunji YAN, Maozhao XIE,
Frontiers in Energy 2010, Volume 4, Issue 2, Pages 198-204 doi: 10.1007/s11708-009-0054-5
Keywords： liquid jet dominant wave number compressibility instability
Yong G. Peng, Gregory M. Janelle
Frontiers of Medicine 2012, Volume 6, Issue 3, Pages 332-337 doi: 10.1007/s11684-012-0212-8
Bedside limited echocardiography, or focused cardiac ultrasound, continues to gain popularity in many emergency rooms, intensive care units, and operating rooms as a rapid method of assessing unstable patients. Effective monitoring of cardiovascular function in conditions like cardiac arrest or near-arrest is the crucial step to guide successful resuscitative efforts. Transesophageal echocardiography (TEE) has emerged as one of the preferred cardiac diagnostic and monitoring modalities in the intraoperative setting due to the fact that it is less invasive than many other monitors, is immediately accessible, and allows for continuous real-time monitoring of cardiac function. However, the minimum training requirements needed for the anesthesia provider to obtain the competency, knowledge, and skills for basic certification in perioperative TEE far exceed those developed for other medical specialties. We believe there is an urgent need to develop (1) practical guidelines for emergent perioperative TEE use for anesthesiologists and (2) a requisite educational curriculum to teach the basic skills necessary to aid in the diagnosis and treatment of cardiac arrest or near-arrest scenarios. The measures elucidated in this report summarize the efforts of the Department of Anesthesiology at the University of Florida in establishing the necessary steps to make this process not only practical, but accessible to all trainees. We hope that these collective efforts will provide more trainees the confidence in utilizing TEE to aid in establishing a diagnosis in critical situations.
Keywords： transesophageal echocardiography curriculum competency training hemodynamic instability
Generation and repair of AID-initiated DNA lesions in B lymphocytes
Zhangguo Chen,Jing H. Wang
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 201-216 doi: 10.1007/s11684-014-0324-4
Activation-induced deaminase (AID) initiates the secondary antibody diversification process in B lymphocytes. In mammalian B cells, this process includes somatic hypermutation (SHM) and class switch recombination (CSR), both of which require AID. AID induces U:G mismatch lesions in DNA that are subsequently converted into point mutations or DNA double stranded breaks during SHM/CSR. In a physiological context, AID targets immunoglobulin (Ig) loci to mediate SHM/CSR. However, recent studies reveal genome-wide access of AID to numerous non-Ig loci. Thus, AID poses a threat to the genome of B cells if AID-initiated DNA lesions cannot be properly repaired. In this review, we focus on the molecular mechanisms that regulate the specificity of AID targeting and the repair pathways responsible for processing AID-initiated DNA lesions.
Keywords： class switch recombination somatic hypermutation activation-induced deaminase DNA repair genomic instability
Nazim Abdul NARIMAN
Frontiers of Structural and Civil Engineering 2017, Volume 11, Issue 2, Pages 131-142 doi: 10.1007/s11709-016-0376-4
Keywords： aeroelastic instability structural damping flutter wind speed bending stiffness torsional stiffness
Frontiers of Mechanical Engineering 2023, Volume 18, Issue 2, doi: 10.1007/s11465-023-0747-1
Keywords： micro-electro-mechanical system capacitive sensor bionics operation instability mechanical and electrical
Flow-Induced Instabilities in Pump-Turbines in China
Zhigang Zuo,Shuhong Liu
Engineering 2017, Volume 3, Issue 4, Pages 504-511 doi: 10.1016/J.ENG.2017.04.010
The stability of pump-turbines is of great importance to the operation of pumped storage power (PSP) stations. Both hydraulic instabilities and operational instabilities have been reported in PSP stations in China. In order to provide a reference to the engineers and scientists working on pump-turbines, this paper summarizes the hydraulic instabilities and performance characteristics that promote the operational instabilities encountered in pump-turbine operations in China. Definitions, analytical methods, numerical and experimental studies, and main results are clarified. Precautions and countermeasures are also provided based on a literature review. The gaps between present studies and the need for engineering practice are pointed out.
Keywords： Pump-turbines Flow-induced instability Pressure fluctuations S-shaped characteristics Positive slopes
Title Author Date Type Operation
Aerodynamic stability evolution tendency of suspension bridges with spans from 1000 to 5000 m
Journal Article
Combustion instability detection using the wavelet detail of pressure fluctuations
JI Junjie, LUO Yonghao
Journal Article
Size-dependent Elastic Instability of Gel CylinderWith Surface Stress
Huang Dianwu,Qiao Ling, Wang Shiji
Journal Article
Modulational Instability of Optical Vortices in Engineered Saturable Media
D.G. Pires, N.M. Litchinitser
Journal Article
Underlying mechanism of the hydrothermal instability of Cu
Nadeen Al-Janabi,Abdullatif Alfutimie,Flor R. Siperstein,Xiaolei Fan
Journal Article
p-Cresyl sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by
Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin
Journal Article
Key technologies of precision demolition blasting of ultra-long urban viaduct in complicated surroundings
Xie Xianqi,Jia Yongsheng,Yao Yingkang,Sun Jinshan,Wu Xinxia,Liu Changbang
Journal Article
Stability of an annular viscous liquid jet in compressible gases with different properties inside and outside of the jet
Chunji YAN, Maozhao XIE,
Journal Article
Emergent limited perioperative transesophageal echocardiography: should new guidelines exist for limited echocardiography training for anesthesiologists?
Yong G. Peng, Gregory M. Janelle
Journal Article
Generation and repair of AID-initiated DNA lesions in B lymphocytes
Zhangguo Chen,Jing H. Wang
Journal Article
A novel structural modification to eliminate the early coupling between bending and torsional mode shapes in a cable stayed bridge
Nazim Abdul NARIMAN
Journal Article
A bionic approach for the mechanical and electrical decoupling of an MEMS capacitive sensor in ultralow force measurement
Journal Article
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